Hello everyone today we will discuss the few reaction mechanism questions with solutions. that are helpful for objective-type question answers solutions in chemical science. we hope you can try to the preparation for any entrance examination level like CSIR NET, GATE, IIT JAM, and others.
Chemclip gives your solution with the proper mechanism of the given organic synthesis. You can practice those questions for the degree program like B.sc or M.sc and correspond to other programs like this.
Now follow the reaction mechanism of reaction:
The reaction is easy to solve, the mechanism is not solved by you. Don’t worry we help you to solve your problem in detail.
Q.3. Find out the major product Y with the proper mechanism.
Answer Question no.3.
Reagent and Reaction mechanism:
This is the one type of selective reaction using an LDA or Lithium diisopropylamide reagent in presence of THF solvent. We know that LDA is a good selective type of reagent, using various sectors in the organic synthesis field for required product making.
This reaction increases the nucleophilicity of the Alpha position Of the given compound. And step number two- which nucleophile is attacked in Benzyl halide on electrophile electrophilic center and release the Br-.
Reaction mechanism:
Solve the organic synthesis of given compounds in the presence of LDA or Lithium diisopropylamide with a reaction mechanism. LDA is a highly selective Regent which is abstracts the Alpha hydrogen in presence of Ester.
In the Reaction mechanism of Q.3, two hydrogens are different acidity and mention given following compound. One alpha beta-unsaturated carbonyl carbon is highly electrophilicity compare to others. That’s why the more acidic Alpha hydrogen abstracted by lithium diisopropylamide (LDA).
LDA reagent morally favors attack in Alpha position in presence of carbonyl group.
Reference:
Carruthers’s book for modern organic synthesis. This book is very very good and better too knowledgeable for any entrance examinations for a research fellow or higher level or advanced level learning of organic synthesis.
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